Alive pathogenic and saprophytic leptospires enter and exit human and mouse macrophages with no intracellular replication

HIGHLIGHTS

  • who: Ignacio Santecchia from the France, Institut Pasteur, Universitu00e9 Citu00e9, Plateforme de Bio-imagerie Ultrastructurale, France Chulalongkorn University, Thailand have published the Article: Alive Pathogenic and Saprophytic Leptospires Enter and Exit Human and Mouse Macrophages With No Intracellular Replication, in the Journal: (JOURNAL)
  • what: These results suggested that, although lysosome-dependent pathways could play a role in the early control of internalized leptospires, they are not the main reason for the major reduction in bacterial loads observed between 3 and 6 h.
  • how: The results showed that CFSE-labeled leptospires can be found . . .

     

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