Trivialities in metabolomics: artifacts in extraction and analysis

HIGHLIGHTS

  • who: . and colleagues from the University of Vienna, Austria have published the article: Trivialities in metabolomics: Artifacts in extraction and analysis, in the Journal: (JOURNAL)
  • what: The aim of this chapter is to highlight the problems of artifact formation in the preanalytical and analytical procedures. Cone and colleagues reported artifact formation in the analysis of metabolites of codeine, when chloroform was used to extract the alkaloids from biological fluids.
  • how: Ion-pairing LC is used in the analysis of alkaloids e_g using long chain sulfonic acids as additive in the mobile phase.
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