Development of halogenated-chalcones bearing with dimethoxy phenyl head as monoamine oxidase-b inhibitors

HIGHLIGHTS

  • who: Nisha Abdul Rehuman and collaborators from the Department of Pharmaceutical Chemistry, DrJoseph Mar Thoma Institute of Pharmaceutical Sciences and Research, Kerala, India Department of Pharmacy, Research Institute of Life Pharmaceutical Sciences, Sunchon National University have published the article: Development of Halogenated-Chalcones Bearing with Dimethoxy Phenyl Head as Monoamine Oxidase-B Inhibitors, in the Journal: Pharmaceuticals 2022, 1152 of 16/09/2022
  • what: This study documented that when compared to MAO-A, two series of dimethoxylated chalcones inhibited MAO-B more potently, and they all had potent MAO-B inhibitory actions with the residual . . .

     

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