Distinct impairments characterizing different adnp mutants reveal aberrant cytoplasmic-nuclear crosstalk

HIGHLIGHTS

  • who: Maram Ganaiem and collaborators from the The Elton Laboratory for Molecular Neuroendocrinology, Department of Human Molecular Genetics Brain Studies, Tel Aviv University, Tel Aviv, Israel have published the research work: Distinct Impairments Characterizing Different ADNP Mutants Reveal Aberrant Cytoplasmic-Nuclear Crosstalk, in the Journal: Cells 2022, 2994 of 21/09/2022
  • what: Distinct cellular phenotypes characterize different ADNP mutants and explain the more severe phenotype of the p.Tyr718*/719* mutant.
  • future: Future studies aimed at translating the current cellular and previous animal studies to clinical practice for better understanding of mutational . . .

     

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