Co-administration of sodium hydrosulfide and tadalafil modulates hypoxia and oxidative stress on bladder dysfunction in a rat model of bladder outlet obstruction _______________________________________________

HIGHLIGHTS

• who: _______________________________________________ and collaborators from the Department of Pharmacology, Faculty of Pharmacy, Cukurova University, Adana, Turkey have published the paper: Co-administration of sodium hydrosulfide and tadalafil modulates hypoxia and oxidative stress on bladder dysfunction in a rat model of bladder outlet obstruction _______________________________________________, in the Journal: (JOURNAL) of April/12,/2022
• what: Combination therapy involving H2S and NO signaling pathways has additive beneficial effects on obstruction-induced bladder dysfunction compared with NaHS or tadalafil alone through an improvement in oxidative stress and hypoxia in the bladder tissue.
• how: Previous data indicated that . . .
  

   

  

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