HIGHLIGHTS
- who: Magdalena Rausch and collaborators from the Department of Clinical Pharmacology and Toxicology, University Hospital Zurich, University of Zurich, Zurich, Switzerland have published the paper: The Farnesoid X Receptor as a Master Regulator of Hepatotoxicity, in the Journal: (JOURNAL)
- what: We provided compelling evidence indicating that hepatic FXR preserves the integrity and function of hepatocytes under chronic and acute stress of varying nature.
- how: Similar observations were made for natural killer T_cells where FXR activation reduced the expression of osteopontin interleukin-1u03b2 and interferon-u03b3 .
SUMMARY
Next to cholesterol . . .
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