Cortical organoids to model microcephaly

HIGHLIGHTS

  • who: Sarah Farcy and colleagues from the (UNIVERSITY) have published the paper: Cortical Organoids to Model Microcephaly, in the Journal: Cells 2022, 11, 2135. of 12/04/2022
  • what: Brain organoid technology, particularly the cortical organoid model, has developed considerably in less than 10 years and has demonstrated its rich potential for modelling microcephaly and for providing valuable information for understanding the mechanisms underlying human brain development.
  • future: More work is required to identify the molecular consequences of ASPM mutation in particular in human bRG cells . More work is now needed to determine . . .

     

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