Reversal of cancer gene expression identifies repurposed drugs for diffuse intrinsic pontine glioma

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  • who: Guisheng Zhao from the Department of Pediatrics and Human Development, Michigan State University, Secchia Center, Room, Michigan StNE, Grand Rapids, MI, USA have published the article: Reversal of cancer gene expression identifies repurposed drugs for diffuse intrinsic pontine glioma, in the Journal: (JOURNAL)
  • what: MMF and MPA had similar efficacy in DIPG cells Since triptolide did not perturb SU-DIPG-IV gene_expression (Fig 3B), and a large dose was required for triamterene, the authors focused on MMF for further analysis. This study demonstrated a deep learning autoencoder for identifying reference controls from other studies . . .

     

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