Early developmental changes of muscle acetylcholine receptors are little influenced by dystrophin absence in mdx mouse

HIGHLIGHTS

• who: Marta Morotti et al. from the Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy have published the paper: Early Developmental Changes of Muscle Acetylcholine Receptors Are Little Influenced by Dystrophin Absence in mdx Mouse, in the Journal: Life 2022, 1861 of 10/Nov/2022
• what: The authors show that openings of both channel subtypes are detected also in the extra-synaptic membrane in young animals, suggesting that during NMJ maturation both AChR isoforms are present in the extra-synaptic region, with the same abundance found at the synapse.
• how . . .
  

   

  

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