Human ipsc-derived cortical neurons displayhomeostatic plasticity

HIGHLIGHTS

  • who: Federica Cordella and colleagues from the Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy have published the research: Human iPSC-Derived Cortical Neurons DisplayHomeostatic Plasticity, in the Journal: (JOURNAL)
  • what: At the post-synaptic level the authors report an increase in the expression of post-synaptic density proteins involved in glutamatergic receptor anchoring. The aim of this study was to investigate, on both sides of the synaptic cleft, the effects of blocking synaptic transmission, using a preparation of cultured human neocortical neurons differentiated from hiPSCs.
  • how: For the analysis . . .

     

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