Antipsychotics function as epigenetic age regulators in human neuroblastoma cells

HIGHLIGHTS

  • who: Jianbin Du from the DepartmentKumamoto University have published the Article: Antipsychotics function as epigenetic age regulators in human neuroblastoma cells, in the Journal: (JOURNAL) of 14/04/2022

SUMMARY

    The sigma-1 receptor is a transmembrane protein located at the endoplasmic_reticulum and modulates calcium signaling via inositol 1,4,5-trisphosphate receptors34. HAL is an antagonist of the sigma-1 receptor and is also suggested to irreversibly inactivate sigma-1 receptor through a HAL metabolite35,36. In the mouse neuroblastoma cell line, NG-108, HAL was suggested to play a role in . . .

     

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