Sex-split analysis of pathology and motor-behavioral outcomes in a mouse model of cln8-batten disease reveals an increased disease burden and trajectory in female

HIGHLIGHTS

  • who: Andrew D. Holmes from the Sioux Falls, SD, USA have published the research work: Sex-split analysis of pathology and motor-behavioral outcomes in a mouse model of CLN8-Batten disease reveals an increased disease burden and trajectory in female, in the Journal: (JOURNAL)
  • what: This study shows sex differences in the progression of CLN8 disease in the Cln8mnd murine model. Taken together, the results from this investigation provide further evidence of sex-dependent differences in lifespan, histopathology, and motor-behavioral outcomes within the Cln8mnd mouse model of Batten disease, and gives insight into . . .

     

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