Type 2 transglutaminase in the nucleus: the new epigenetic face of a cytoplasmic enzyme

HIGHLIGHTS

• who: Federica Rossin from the Department of Biology, University of Rome u2018Tor Vergata`, Via Della Ricerca Scientifica, Rome, Italy have published the research: Type 2 transglutaminase in the nucleus: the new epigenetic face of a cytoplasmic enzyme, in the Journal: (JOURNAL)
• what: In this study it was shown that the glutamine 5 of the histone 3 (H3Q5) acts as the binding_site for the serotonylation by TG2.
• how: At the molecular level the results indicated that the TG2 is responsible for the activation of the heat shock factor 1 (HSF1) the main transcriptional factor . . .
  

   

  

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