Epigenetic histone acetylation modulating prenatal poly i:c induced neuroinflammation in the prefrontal cortex of rats: a study in a maternal immune activation model

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  • who: Chao Deng from the Columbia University, United States have published the paper: Epigenetic histone acetylation modulating prenatal Poly I:C induced neuroinflammation in the prefrontal cortex of rats: a study in a maternal immune activation model, in the Journal: (JOURNAL) of 28/Nov/2022
  • what: Although prenatal Poly I:C exposure induced abnormal expressions of neurotransmitter receptors Grin2a, Gabrb3, and Htr2a in the PFC (Su et_al, 2022), this study showed no direct H3 and H4 histone acetylation at the promoter regions of genes encoding these neurotransmitter receptors. Using an MIA model, this study provided . . .

     

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