Chronic ampk activation reduces the expression and alters distribution of synaptic proteins in neuronal sh-sy5y cells

HIGHLIGHTS

  • who: Alex J. T. Yang et al. from the Department of Health Sciences, Brock University, StCatharines, ON L S , Canada have published the article: Chronic AMPK Activation Reduces the Expression and Alters Distribution of Synaptic Proteins in Neuronal SH-SY5Y Cells, in the Journal: Cells 2022, 2354 of 31/07/2022
  • what: This study examined the effect of activation on markers of synaptic function and growth. Specifically, the authors demonstrate that 5 days of AMPK activation reduced total content of a ubiquitous synaptic marker, synaptophysin, marker of postsynaptic stability Homer-1, and the major neurotrophic . . .

     

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