Valproic acid inhibits progressive hereditary hearing loss in a kcnq4 variant model through hdac1 suppression

HIGHLIGHTS

  • who: Yoon Seok Nam et al. from the Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School and Chonnam National University Hospital, Gwangju, Republic of Korea have published the paper: Valproic Acid Inhibits Progressive Hereditary Hearing Loss in a KCNQ4 Variant Model through HDAC1 Suppression, in the Journal: (JOURNAL)
  • what: The authors propose that HDAC1 is an the binding of KCNQ4 to HSP90u03b2. The study showed that the upregulation of KCNQ4 and HSP90u03b2 by VPA . The study showed that the progression of hearing deterioration could be inhibited by VPA in a KCNQ4 . . .

     

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