Long-term hyperglycemia causes depressive behaviors in mice with hypoactive glutamatergic activity in the medial prefrontal cortex, which is not reversed by insulin treatment

HIGHLIGHTS

  • who: Ji Hyeong Baek and collaborators from the Department of Anatomy and Convergence Medical Sciences, Institute of Health Sciences, Tyrosine Peptide National University Medical School, Jinju-daero , Beongil, Jinju, Republic of Korea have published the research work: Long-Term Hyperglycemia Causes Depressive Behaviors in Mice with Hypoactive Glutamatergic Activity in the Medial Prefrontal Cortex, Which Is Not Reversed by Insulin Treatment, in the Journal: Cells 2022, x of 31/Oct/2022
  • what: The authors first identified depressive-behavior-associated alterations in the mouse brain resulting from streptozotocin (STZ)-induced hyperglycemia. The authors showed that long . . .

     

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