Ybx1 integration of oncogenic pi3k/mtor signalling regulates the fitness of malignant epithelial cells

HIGHLIGHTS

  • who: Yuchen Bai from the models were characterised previouslyBoth animal strains were established on a C BL/, background and males and females equally used at , months old. The animals were monitored according to the Peter Mac Animal Ethics guidelines and maximal tumour size and burden were not exceeded. The patient samples were collected under the University of Western Australia Human Research Ethics Approval number RA/4/1/, and made into tissue arrays. Informed consent was obtained by all participants. Established cell lines derived from patients with HPV-negative (, and SCC25) HNC were used to generate orthotopic xenografts . . .

     

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