Breadth of sars-cov-2 neutralization and protection induced by a nanoparticle vaccine

HIGHLIGHTS

  • who: Dapeng Li from the Antibody-dependent NK cell degranulation assay Cell-surface expression of CD107a was used as a marker for NK cell degranulation, a prerequisite process for ADCC (Ferrari et_al, ), was performed as previously described (Pino et_al, )Briefly, target cells were either Vero , cells after a , day-infection with SARSCo, USA-WA1/, or T cells, days post transfection with a SARS-Co, S protein (D614) expression plasmid. NK cells were purified from peripheral blood of a healthy human volunteer, from the External Quality Assurance Program Oversight Laboratory (EQAPOL)55, in compliance with Institutional Review Board . . .

     

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