Il-17a expression by both t cells and non-t cells contribute to hsv-il-2-induced cns demyelination

HIGHLIGHTS

• who: Satoshi Hirose from the Georgia State University, United States have published the Article: IL-17A expression by both T cells and non-T cells contribute to HSV-IL-2-induced CNS demyelination, in the Journal: (JOURNAL)
• what: All mice used in frontiersin.org 10.3389/fimmu.2023.1102486 this study have a B6 background and were bred in-house. The authors have shown the absence of CNS demyelination in IL-17A-/- mice following ocular infection with HSV-IL-2 virus, while transfer of T_cells from WT mice to recipient IL-17A-/- mice caused CNS . . .
  

   

  

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