The role of (pro)renin receptor and its soluble form in cardiovascular diseases

HIGHLIGHTS

  • who: Boyang Wang from the of Otago, New Zealand Medical College, China have published the paper: The role of (pro)renin receptor and its soluble form in cardiovascular diseases, in the Journal: (JOURNAL)
  • how: These results indicated that there may be positive feedback between PRR and COX2 and it played an important role in Ang II-dependent hypertension.
  • future: V-ATPase dysfunction caused by PRR absence commonly occurs prenatally in PRR knockouts which suggests that appropriate PRR blockade in the therapy of hypertension may not lead to a serious adverse consequence in adults . . .

     

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