Gimap7 induces oxidative stress and apoptosis of ovarian granulosa cells in polycystic ovary syndrome by inhibiting sonic hedgehog signalling pathway

HIGHLIGHTS

  • who: Anran Xu from the Jinan, Shandong, Peopleu2019s Republic of China have published the research work: GIMAP7 induces oxidative stress and apoptosis of ovarian granulosa cells in polycystic ovary syndrome by inhibiting sonic hedgehog signalling pathway, in the Journal: (JOURNAL)
  • what: The aim of this study was to investigate the role of GTPase immunity-associated protein (GIMAP) 7 in PCOS. The authors demonstrated that GIMAP7 is upregulated in PCOS.
  • how: The data showed that GIMAP7 was mainly located in granulosa cells and was abundantly expressed in the ovarian granulosa cells of PCOS rats . . .

     

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