Estrogen receptor β/substance p signaling in spinal cord mediates antinociceptive effect in a mouse model of discogenic low back pain

HIGHLIGHTS

  • who: Xiao-Xing Song from the The University of Texas at Austin, United States have published the research: Estrogen receptor u03b2/substance P signaling in spinal cord mediates antinociceptive effect in a mouse model of discogenic low back pain, in the Journal: (JOURNAL) of 23/01/2023
  • what: The authors investigated the antinociceptive effects of selective ERu03b2 agonists on DLBP-related behavior by regulating substance P in spinal cord and dorsal root ganglia. This study reports that immunofluorescence examination exhibited colocalization of ERu03b2 and substance P at both cytoplasm and nucleus Frontiers in Cellular Neuroscience . . .

     

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