HIGHLIGHTS
SUMMARY
It has not been examined whether physical activity and sedentary behavior are underlying mechanisms in the association between working from home and musculoskeletal pain. Longitudinal information on work situation (location, home, hybrid), physical activity, sedentary behavior, and musculoskeletal pain was collected among 28,586 workers. Analysis of physical activity/sedentary behavior as mediators of the association between working from home and musculoskeletal pain was performed using multilevel structural equation modeling. Home and hybrid workers were more likely to have pain in the upper musculoskeletal system during the COVID-19 pandemic than location Frontiers in . . .
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