The influence of the electron density in acyl protecting groups on the selectivity of galactose formation

HIGHLIGHTS

  • who: Kim Greis and colleagues from the (UNIVERSITY) have published the research: The Influence of the Electron Density in Acyl Protecting Groups on the Selectivity of Galactose Formation, in the Journal: (JOURNAL) of October/27,/2022
  • what: This study shows that electron-donating substituents on participating acyl protecting groups increase the efficiency of remote participation, leading to a higher u03b1-selectivity in glycosylation reactions, as shown for pivaloyl groups.

SUMMARY

    While the position of the acyl protecting group and the influence of nucleophile strength have been investigated before,10,15 the . . .

     

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