Fty720 attenuates lps-induced inflammatory bone loss by inhibiting osteoclastogenesis via the nf- κ b and hdac4/ atf pathways

HIGHLIGHTS

• who: ATF Pathways and collaborators from the Medical University, Taiyuan, China have published the article: FTY720 Attenuates LPS-Induced Inflammatory Bone Loss by Inhibiting Osteoclastogenesis via the NF- u03ba B and HDAC4/ ATF Pathways, in the Journal: Journal of Immunology Research of 19/07/2022
• what: The research shows that OC differentiation is significantly reduced in bone marrow mononuclear cell cultures derived from ATF4 knockout mice . The authors investigated how FTY720 affects osteoclastogenesis and OC function in_vitro and LPS-induced bone loss in_vivo.
• how: The animals used in the experiment were C57BL/6 . . .
  

   

  

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