HIGHLIGHTS
- who: Dirk Tu00e4nzler et al. from the Department of Pharmaceutical Chemistry and Bioanalytics, Institute of Pharmacy, Martin Luther University University of Leipzig, Leipzig, Saxony, Germany have published the paper: Effects of theophylline on ADCY5 activationu2014From cellular studies to improved therapeutic options for ADCY5-related dyskinesia patients, in the Journal: PLOS ONE of August/26,/2022
- what: The authors show the effects of the three purine derivatives caffeine theophylline and istradefylline on cAMP production by adenylyl cyclase 5 (ADCY5)-overexpressing cell lines. The authors show that cAMP levels in ADCY5-overexpressing cells were reduced with all . . .
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