HIGHLIGHTS
- who: Rika Kojima from the Department of Clinical Neuroscience, Neuro Svenningsson, Karolinska Institutet, , Stockholm, Sweden have published the article: Prosaposin Reduces u03b1-Synuclein in Cells and Saposin C Dislodges it from Glucosylceramide-enriched Lipid Membranes, in the Journal: (JOURNAL)
- what: The authors aim to elucidate the neuroprotective roles of PSAP and in PD by evaluating their effects on accumulation in human neuroblastoma cells. The study shows that PSAP regulates the levels of u03b1-synuclein, which is attributed to saposin C`s function to promote u03b1-synuclein clearance by dissociating u03b1-synuclein from the lipid membranes . . .
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