Mannan-binding lectin serine protease-2 (masp-2) in human kidney and its relevance for proteolytic activation of the epithelial sodium channel

HIGHLIGHTS

• who: Rikke Zachar from the DepartmentUniversity of have published the Article: Mannan-binding lectin serine protease-2 (MASP-2) in human kidney and its relevance for proteolytic activation of the epithelial sodium channel, in the Journal: Scientific Reports Scientific Reports
• what: The authors showed that MASP-2 can activate ENaC in_vitro when co-expressed in Xenopus oocytes, but not in MASP2 transfected M1 cells.

SUMMARY

Co‑expresseion of MASP‑2 activates ENaC in_vitro in Xenopus oocytes, but not in a stable cell line and no difference in γENaC cleavage products of . . .

 



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