Endogenous retroviruses and tdp-43 proteinopathy form a sustaining feedback driving intercellular spread of drosophila neurodegeneration

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  • who: Yung-Heng Chang from the Fly strains and husbandry We obtained SPG-Gal, (R, Gal4, #50472) and UAS-myr-RFP (#7119) from Bloomington Drosophila Stock CenterThe hTDP- , and UAS-hTDP-43-, were generous gifts from Professor David Morton (Oregon Health and Science University) and Professor Jane Y. Wu (Northwestern University School of Medicine). The following stocks, UAS-GFP-IR, UAS-mdg4-IR (also known as UAS-gypsy-IR in previous studies), UAS-hTDP-43, tub-Gal80ts and UAS-mCD8-GFP were used in our previous studies12, , . To prevent artifacts from genetic variation between groups, all strains . . .

     

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