Slow growing behavior in african trypanosomes during adipose tissue colonization

HIGHLIGHTS

  • who: Sandra Trindade from the Divisions/per day have published the paper: Slow growing behavior in African trypanosomes during adipose tissue colonization, in the Journal: (JOURNAL) of 17/08/2022
  • what: The authors propose that in adipose_tissue, a subpopulation of T. brucei parasites acquire a slow growing behavior, which contributes to disease chronicity and treatment failure. The authors use mathematical modelling to determine key parameters that govern T. brucei chronic infections taking into account the existence of tissue reservoirs. Together with previous knowledge that ATFs are metabolically distinct from their blood counterparts3, the authors propose . . .

     

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