Effect of the intratumoral microbiota on spatial and cellular heterogeneity in cancer

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  • who: Jorge Luis Galeano Niamp#x000F1 and o from the (UNIVERSITY) have published the Article: Effect of the intratumoral microbiota on spatial and cellular heterogeneity in cancer, in the Journal: (JOURNAL) of 10/Oct/2022
  • what: Using GeoMx digital spatial profiling6, the authors show that bacterial communities populate microniches that are less vascularized, highly immunou2011suppressive and associated with malignant cells with lower levels of Ki-67 as compared to bacterianegative tumour regions. Through functional studies, the authors show that cancer cells that are infected with bacteria invade their surrounding environment as single cells and recruit . . .

     

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