A novel lncrna mdhdh suppresses glioblastoma multiforme by acting as a scaffold for mdh2 and psma1 to regulate nad+ metabolism and autophagy

HIGHLIGHTS

  • who: Dong He from the datasets and collected clinical samples from Shandong Provincial Hospital, affiliated with Shandong UniversityFunctional assays, including FISH/CISH, CCK8, EdU, wound healing, and transwell assays, were used to determine the cellular/subcellular localization, tissue expression profile and anti-oncogenic role of MDHDH. Furthermore, RNA pulldown, University, Jinan, Shandong, P.R. China have published the research: A novel lncRNA MDHDH suppresses glioblastoma multiforme by acting as a scaffold for MDH2 and PSMA1 to regulate NAD+ metabolism and autophagy, in the Journal: (JOURNAL)
  • what: Animal experiments were conducted to determine the antitumorigenic role . . .

     

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