HIGHLIGHTS
- who: Elisavet Vlachonikola and colleagues from the National Institute of Genomic Medicine (INMEGEN), Mexico Department of, Development and Molecular Biology, School of Biology, Aristotle, University have published the research: T cell receptor gene repertoire profiles in subgroups of patients with chronic lymphocytic leukemia bearing distinct genomic aberrations, in the Journal: (JOURNAL)
- what: The authors report oligoclonality in all groups of patients with distinct recurrent genomic aberrations, albeit more pronounced in cases bearing copy number aberrations (CNAs), particularly trisomy 12. Relapses still occur and CLL remains an incurable malignancy, highlighting the need for alternative therapeutic approaches . . .
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