HIGHLIGHTS
- who: December and colleagues from the Maastricht University, Netherlands Germany have published the article: TREK-1 in the heart: Potential physiological and pathophysiological roles, in the Journal: (JOURNAL)
SUMMARY
Knowing its electrophysiological properties, channel open at rest and outwardly rectifying current, led to the inference that this channel must hyperpolarize the resting membrane potential and/or shorten the APD of cardiac cells but this has never been shown (Benoist et_al, 2014; Kelly et_al, 2006). There are some evidences of the role of TREK-1 remodeling in the development of some arrhythmias (Benoist et_al . . .
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