Pgd2 displays distinct effects in diffuse large b-cell lymphoma depending on different concentrations

HIGHLIGHTS

  • who: Shunfeng Hu from the (UNIVERSITY) have published the article: PGD2 displays distinct effects in diffuse large B-cell lymphoma depending on different concentrations, in the Journal: (JOURNAL) of 27/Dec/2022
  • what: The investigation showed that high-concentration PGD2 induced cell apoptosis, but significantly increased the expression of anti-apoptotic factor Bcl-2 in DLBCL cells (Fig 4F). The authors demonstrated that high-concentration Cell Death Discovery 9:39 Cell Death Discovery 9:39 9 PGD2 exerted anti-tumor effects through inducing ROS accumulation and then DNA damage in DLBCL.
  • how: These . . .

     

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