Fusion of wild-type mesoangioblasts with myotubes of mtdna mutation carriers leads to a proportional reduction in mtdna mutation load

HIGHLIGHTS

• who: Ruby Zelissen and collaborators from the Department of Toxicogenomics, Maastricht University Medical Centre+, HX Maastricht, The Netherlands have published the Article: Fusion of Wild-Type Mesoangioblasts with Myotubes of mtDNA Mutation Carriers Leads to a Proportional Reduction in mtDNA Mutation Load, in the Journal: (JOURNAL)
• what: The proportional reduction in mtDNA mutation load in vitro after fusion is promising in the context of muscle stem cell therapy for mtDNA mutation carriers in vivo in which the authors propose the same strategy using autologous wild-type mesoangioblasts. The authors aim to demonstrate that wild-type . . .
  

   

  

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