Amelioration of high-fat diet (hfd) + ccl4 induced nash/nafld in cf-1 mice by activation of sirt-1 using cinnamoyl sulfonamide hydroxamate derivatives: in-silico molecular modelling and in-vivo prediction

HIGHLIGHTS

• who: Nalini Sodum from the Department of Pharmacology, Manipal College Education, Manipal, Karnataka, India have published the Article: Amelioration of high-fat diet (HFD)u2009+u2009CCl4 induced NASH/NAFLD in CF-1 mice by activation of SIRT-1 using cinnamoyl sulfonamide hydroxamate derivatives: in-silico molecular modelling and in-vivo prediction, in the Journal: (JOURNAL)
• what: This study was carried out using different in-silico tools such as molecular docking and molecular dynamics from Schru00f6dinger, maestro, LLC software. This study was designed to check the effect of cinnamyl sulfonamide hydroxamate derivatives for treating NASH.
 



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