HIGHLIGHTS
- who: Yanan Zhai from the (UNIVERSITY) have published the article: Longitudinal single-cell transcriptomics reveals distinct patterns of recurrence in acute myeloid leukemia, in the Journal: (JOURNAL)
- what: The authors investigated the clonal heterogeneity of diagnosis (Dx) and relapse (Re) pairs at genetic and transcriptional levels and unveiled the underlying pathways and genes contributing to recurrence. The study provides novel insights into recurrence and unveils vulnerabilities that could serve as new entry points for targeting relapse AMLs. Dxu2011Re transcriptomic changes are patient specific Given this high intra- and inter-patient heterogeneity, the authors focused on . . .
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