S100a11 activates the pentose phosphate pathway to induce malignant biological behaviour of pancreatic ductal adenocarcinoma

HIGHLIGHTS

• who: Xue Zeng from the Animal experiments Five-week-old BALB/c-nu/nu female mice were purchased from Shanghai Laboratory Animal Center (Chinese Academy of Science)All animal procedures were approved by the Institutional Animal Care Committee of China Medical University and complied with its guidelines. Mice were randomly assigned to subcutaneous injection with S , knockdown or control cells (n=3). Six weeks after injection, mice were scored for the presence of palpable tumours. The dose of cells injected into the mice without tumours was plotted and the slope of the graph was used to estimate . . .
  

   

  

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