In vitro grafting of hepatic spheroids and organoids on a microfluidic vascular bed

HIGHLIGHTS

  • who: Flavio Bonanini from the Mimetas, Leiden, The Netherlands have published the research work: In vitro grafting of hepatic spheroids and organoids on a microfluidic vascular bed, in the Journal: (JOURNAL)
  • what: The authors exclusively utilized collagen I to pattern the microfluidics; however, several different ECM gels have been reported in conjunction with phaseguide technology . The authors demonstrated clear feasibility of in_vitro grafting by example of vascularization of liver tissue. The authors propose, therefore, a viable, robust, easy-to-use, and versatile platform to develop vascularized in_vitro cultures. Although the authors focused on the liver . . .

     

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