Do cytotoxicity and cell death cause false positive results in the in vitro comet assay?

HIGHLIGHTS

  • who: Amaya Azqueta from the Department of Pharmacology and Toxicology, University of Navarra, C/Irunlarrea, Pamplona, Spain and IdiSNA, Navarra Institute for Health Research have published the research work: Do cytotoxicity and cell death cause false positive results in the in vitro comet assay?, in the Journal: (JOURNAL)
  • what: The aim of this review is to assess whether DNA damage measured by the comet assay is biased by concurrent cytotoxicity or cell death in cell culture studies. The authors provide a brief overview of the assays used to detect cytotoxicity and cell death. The authors . . .

     

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