The heterochromatin protein 1 is a regulator in rna splicing precision deficient in ulcerative colitis

HIGHLIGHTS

• who: Jorge Mata-Garrido from the Mouse models C BL/, Cbx3fl/fl mice (provided by Dr Florence Cammas, IRCM, Montpellier, France) were crossed with Villin-Cre, mice (provided by Dr Cohen-Tannoudji, Institut Pasteur, Paris, France) to produce the C BL/, Villin-creERT2:Cbx3-/- mouse model (this study)C BL/, Heterozygote LmnaG G/G G mice (here referred as HGPS mice) were provided by Dr Maria Eriksson (Karolinska Institutet, Sweden). Male and female mice were fed by a standard diet (SD) rodent chow (, Teklad Global, % Protein Rodent Diet, Harlan) composed of, % carbohydrate fed ad libitum. The animals . . .
  

   

  

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