Super-resolution quanti cation of t2dm-induced mitochondrial morphology changes and their implications in pharmacodynamics of metformin and sorafenib

HIGHLIGHTS

  • who: Morphology Changes and collaborators from the School, Sichuan University, Chengdu, China, Dean`s Office, West China Hospital, Sichuan University, Chengdu, China have published the Article: Super-Resolution Quanti cation of T2DM-Induced Mitochondrial Morphology Changes and Their Implications in Pharmacodynamics of Metformin and Sorafenib, in the Journal: (JOURNAL)
  • what: The authors used a super-sensitive method, SIM, to examine the morphological changes in mitochondria.
  • how: Taken together based on the superresolution of SIM the authors proposed a new strategy for studying T2DM and evaluating the pharmacodynamics of related drugs by quantifying mitochondrial . . .

     

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