HIGHLIGHTS
SUMMARY
Although the role of the tear film and corneal epithelial_cells have been extensively described, that of LG and conjunctiva remains far less explored clinically, even though these are considered to be drivers of the inflammatory milieu. such as ocular allergies, rosacea, Sjögren`s syndrome (SS), graft versus host disease (GVHD), different cicatrizing conjunctivitis syndromes and more. The authors will review the OSID with experimental and in_vivo evidence for their existence, immunological basis, target tissues and implications. Evidence for this comes from mouse models of dry eye, on which CD4 T_cells were transferred to . . .
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