A mrna vaccine encoding for a rbd 60-mer nanoparticle elicits neutralizing antibodies and protective immunity against the sars-cov-2 delta variant in transgenic k18-hace2 mice

HIGHLIGHTS

  • who: Pascal Brandys from the University of Copenhagen, Denmark have published the research work: A mRNA Vaccine Encoding for a RBD 60-mer Nanoparticle Elicits Neutralizing Antibodies and Protective Immunity Against the SARS-CoV-2 Delta Variant in Transgenic K18-hACE2 Mice, in the Journal: (JOURNAL)
  • what: The aim of these various designs is to increase antigen trafficking into draining lymph nodes and to promote B cell receptor clustering and B cell activation. The authors report a messenger RNA encoding for a designed nanoparticle in which multimeric RBDDelta is displayed onto a protein scaffold composed . . .

     

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