Perilipin 2 protects against lipotoxicity-induced islet fibrosis by inducing islet stellate cell activation phenotype changes

HIGHLIGHTS

• who: Yunting Zhou and colleagues from the Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China have published the research work: Perilipin 2 Protects against Lipotoxicity-Induced Islet Fibrosis by Inducing Islet Stellate Cell Activation Phenotype Changes, in the Journal: BioMed Research International of 24/Dec/2021
• what: The aim of this present study is to investigate the effects of perilipin family on lipotoxicity-induced islet dysfunction by mediating ISCs activation and its intracellular signaling mechanism.
• how: The results showed that PA-treated ISCs cultured in medium had a significantly faster . . .
  

   

  

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