A snx1 – snx2 vapb partnership regulates endosomal membrane rewiring in response to nutritional stress

HIGHLIGHTS

  • who: A SNX and colleagues from the (UNIVERSITY) have published the Article: A SNX1 - SNX2 VAPB partnership regulates endosomal membrane rewiring in response to nutritional stress, in the Journal: (JOURNAL)
  • what: The authors show that starvation-induced autophagy associates with an increase in endosomal tubulation and networking, a dynamic process dependent on the endosomal protein SNX1. The authors report that upon starvation, SNX2, an endosomal partner of SNX1, patterns to SNX1-positive tubules and triggers membrane tethering between the SNX1 endosomal tubules and autophagosome-initiating ER platforms via the ER protein VAPB. The authors show . . .

     

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