Shionone-targeted pneumolysin to ameliorate acute lung injury induced by streptococcus pneumoniae in vivo and in vitro

HIGHLIGHTS

• who: Runbao Du and collaborators from the The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China have published the Article: Shionone-Targeted Pneumolysin to Ameliorate Acute Lung Injury Induced by Streptococcus pneumoniae In Vivo and In Vitro, in the Journal: Molecules 2022, 27, x FOR PEER REVIEW of 23/09/2022
• what: In this study the anti-infective effect of was explored. In this study, the elementary mechanism of shionone against S. pneumoniae infection was explored firstly mainly via hemolysis tests, oligomerization inhibition assays, and molecular docking in_vitro and establishing acute lung injury (ALI . . .
  

   

  

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