An interaction between synapsin and c9orf72 regulates excitatory synapses and is impaired in als/ftd

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  • who: Claudia S. Bauer from the Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, a Glossop Road, Sheffield , HQ, UK have published the article: An interaction between synapsin and C9orf72 regulates excitatory synapses and is impaired in ALS/FTD, in the Journal: (JOURNAL)
  • what: The authors demonstrate that C9orf72 haploinsufficiency impairs excitatory synapses in_vitro and in_vivo as well as in post-mortem brain of C9ALS/FTD patients. This study shows that C9orf72 plays a cell-autonomous role in the regulation of neurotransmission at excitatory synapses. The authors show that C9orf72 interacts . . .

     

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